Principles of Pharmacology
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Publication Date: 2011
Availability: In Stock
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ISBN/ISSN: 9781608312702

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Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, Third Edition, is a primary textbook for a first course in pharmacology. It offers an integrated mechanism-based and systems-based approach, incorporating the cell biology, biochemistry, physiology, and pathophysiology of organ systems. The completely updated Third Edition features content reflecting current research findings, more than 400 full-color illustrations, Drug Summary Tables, and increased coverage of drug metabolism and the treatment of mycobacterial infections.

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  • NEW: Incorporates full-color illustrations throughout, suiting the needs of visual learners and more effectively presenting concepts covered in the narrative  
  • NEW: Features increased coverage of drug metabolism and the treatment of mycobacterial infections, as well as updated cases and questions, all within the scope of clinical relevance
  • Provides additional resources via thePoint, including fully searchable eBook and faculty image bank, test generator, and PowerPoint slides
  • Represents more than a drug dictionary: Golan first establishes a foundation for normal physiology, then covers pathophysiology, and concludes with pharmacology for a thorough understanding of the connections between each
  • Features a signature pedagogical sequence for optimal learning and review: clinical scenario, questions, content, answers to questions, and conclusions
  • Delivers content appropriate for students through a uniquely collaborative authorship consisting of medical students and faculty

David E. Golan MD, PhD
Professor of Biological Chemistry, Harvard Medical School, Boston, MA

April W. Armstrong MD
Clinical Fellow, Department of Dermatology, Harvard Medical School, Boston, MA

Armen H. Tashjian Jr., MD
Professor Emeritus of Toxicology and Pharmacology, Harvard School of Public Health, Boston, MA


Edition: 3
ISBN/ISSN: 9781608312702
Product Format: Softbound
Trim Size: 8.375 x 10.875
Pages: 976
Pub Date: 2011
Weight: 4.15

Section 1. Fundamental Principles of Pharmacology

Chapter 1. Drug-Receptor Interactions
Chapter 2. Pharmacodynamics
Chapter 3. Pharmacokinetics
Chapter 4. Drug Metabolism
Chapter 5. Drug Toxicity
Chapter 6  Pharmacogenomics
 
Section 2. Principles of Neuropharmacology
Section 2a. Fundamental Principles of Neuropharmacology
Chapter 7. Principles of Cellular Excitability and Electrochemical Transmission
Chapter 8. Principles of Nervous System Physiology and Pharmacology
Section 2b. Principles of Autonomic and Peripheral Nervous System Pharmacology
Chapter 9. Cholinergic Pharmacology
Chapter 10. Adrenergic Pharmacology
Chapter 11. Local Anesthetic Pharmacology
Section 2c. Principles of Central Nervous System Pharmacology
Chapter 12. Pharmacology of GABAergic and Glutamatergic Neurotransmission
Chapter 13. Pharmacology of Dopaminergic Neurotransmission
Chapter 14. Pharmacology of Serotonergic and Central Adrenergic Neurotransmission
Chapter 15. Pharmacology of Abnormal Electrical Neurotransmission in the Central Nervous System
Chapter 16. General Anesthetic Pharmacology
Chapter 17. Pharmacology of Analgesia
Chapter 18. Pharmacology of Chemical Dependence and Addiction
 
Section 3. Principles of Cardiovascular Pharmacology
Chapter 19. Pharmacology of Cholesterol and Lipoprotein Metabolism
Chapter 20. Pharmacology of Volume Regulation
Chapter 21. Pharmacology of Vascular Tone
Chapter 22. Pharmacology of Hemostasis and Thrombosis
Chapter 23. Pharmacology of Cardiac Rhythm
Chapter 24. Pharmacology of Cardiac Contractility
Chapter 25. Integrative Cardiovascular Pharmacology: Hypertension, Ischemic Heart Disease, and Heart Failure
 
Section 4. Principles of Endocrine Pharmacology
Chapter 26. Pharmacology of the Hypothalamus and Pituitary Gland
Chapter 27. Pharmacology of the Thyroid Gland
Chapter 28. Pharmacology of the Adrenal Cortex
Chapter 29. Pharmacology of Reproduction
Chapter 30. Pharmacology of the Endocrine Pancreas
Chapter 31. Pharmacology of Bone Mineral Homeostasis
 
Section 5. Principles of Chemotherapy
Chapter 32. Principles of Antimicrobial and Antineoplastic Pharmacology
Chapter 33. Pharmacology of Bacterial Infections: DNA Replication, Transcription, and Translation
Chapter 34. Pharmacology of Bacterial and Mycobacterial Infections: Cell Wall Synthesis
Chapter 35. Pharmacology of Fungal Infections
Chapter 36. Pharmacology of Parasitic Infections
Chapter 37. Pharmacology of Viral Infections
Chapter 38. Pharmacology of Cancer: Genome Synthesis, Stability, and Maintenance
Chapter 39. Pharmacology of Cancer: Signal Transduction
Chapter 40. Principles of Combination Chemotherapy
 
Section 6. Principles of Inflammation and Immune Pharmacology
Chapter 41. Principles of Inflammation and the Immune System
Chapter 42. Pharmacology of Eicosanoids
Chapter 43. Histamine Pharmacology
Chapter 44. Pharmacology of Hematopoiesis and Immunomodulation
Chapter 45. Pharmacology of Immunosuppression
Chapter 46. Integrative Inflammation Pharmacology: Peptic Ulcer Disease
Chapter 47. Integrative Inflammation Pharmacology: Asthma
Chapter 48. Integrative Inflammation Pharmacology: Gout
 
Section 7. Fundamentals of Drug Development and Regulation
Chapter 49. Drug Discovery and Preclinical Development
Chapter 50. Clinical Drug Evaluation and Regulatory Approval
Chapter 51. Systematic Detection of Adverse Events in Marketed Drugs
 
Section 8. Poisoning by Drugs and Environmental Toxins
 
Chapter 52. Poisoning by Drugs and Environmental Toxins
 
Section 9. Frontiers in Pharmacology
Chapter 53. Protein-Based Therapies
Chapter 54. Drug Delivery Modalities
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