Fundamental Immunology

Description

Fundamental Immunology

Seventh Edition

This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.

Now full-color throughout the book’s fully revised and updated content reflects the latest advances in the field. Current insights enhance readers’ understanding of immune system function. The text’s unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text with all references linked to PubMed.

Look inside and discover…

• Fully revised and updated content reflects the latest advances in the field.

• Current insights enhance readers’ understanding of immune system function

• Unique approach bridges the gap between basic immunology and the disease process.

• Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment.

• Abundant illustrations and tables deliver essential information at a glance.

PLUS…

A convenient companion website features the fully searchable text with all references linked to PubMed.

Pick up your copy today!

Features

Look inside and discover…
• Fully revised and updated content reflects the latest advances in the field.
• Current insights enhance readers’ understanding of immune system function
• Unique approach bridges the gap between basic immunology and the disease process.
• Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment.
• Abundant illustrations and tables deliver essential information at a glance.

PLUS…
A convenient companion website features the fully searchable text with all references linked to PubMed

About the Author(s)

William E Paul
Chief, Laboratory of Immunology; Chief, Cytokine Biology Unit, L1; National Institutes of Health Distinguished Investigator, National Institute of Allergy and Infectious Diseases, Bethesda, MD

Specs

Edition: Seventh
Product Format: Hardbound
ISBN: 9781451117837
Trim Size: 8.375 x 10.875
Pages: 1312
Pub Date: Dec 11, 2012
Weight: 5.0

Section I. Introduction to Immunology Â 1Â Â Â Â Â Â Â Â Â The Immune SystemÂ Â William E. Paul Â 2Â Â Â Â Â Â Â Â Â History of Immunology Â Â Â Â Â Â Â Â Â Â Â Steven GreenbergÂ Â Â Â Â Â Â Section II. Organization and Evolution of the Immune System Â 3Â Â Â Â Â Â Â Â Â Lymphoid Tissues and Organs Â Â Â Â Â Â Â Â Â Â Â Eitan M. Akirav, Noelia Alonso-Gonzalez, Lucy A. Truman, and Nancy H. RuddleÂ Â Â Â Â Â Â Â Â Â Â 4Â Â Â Â Â Â Â Â Â Evolution of the Immune System Â Â Â Â Â Â Â Â Â Â Â Martin F. FlajnikÂ Â Â Â Â Â Â Â Â Section III. Immunoglobulins and B Lymphocytes Â 5Â Â Â Â Â Â Â Â Â Immunoglobulins: Structure and Function Â Â Â Â Â Â Â Â Â Â Â Harry W. SchroederÂ Â Â Â 6Â Â Â Â Â Â Â Â Â Immunoglobulins: Molecular Genetics Â Â Â Â Â Â Â Â Â Â Â Edward E. Max and Sebastian FugmannÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â 7Â Â Â Â Â Â Â Â Â Antigen-Antibody Reactions Â Â Â Â Â Â Â Â Â Â Â Jay A. Berzofsky and Ira BerkowerÂ Â Â 8Â Â Â Â Â Â Â Â Â B Lymphocyte Development Â Â Â Â Â Â Â Â Â Â Â Richard R.Â HardyÂ Â Â Â Â Â 9Â Â Â Â Â Â Â Â Â B Lymphocyte Receptors, Signaling Mechanisms, and Activation Akanksha Chaturvedi, Angel Davey, Wanli Liu, Hae Won Sohn, and Susan K. PierceÂ Â Â Â Â Â Â 10Â Â Â Â Â Â Â B Lymphocyte Responses Michael McHeyzer-WilliamsÂ Â Section IV. T Lymphocytes Â 11Â Â Â Â Â Â Â T Lymphocyte Receptors Â Â Â Â Â Â Â Â Â Â Â Mark M. DavisÂ Â Â Â Â Â Â Â Â Â Â Â 12Â Â Â Â Â Â Â T Lymphocyte Signaling Mechanisms Â Â Â Â Â Â Â Â Â Â Â Takashi SaitoÂ Â Â 13Â Â Â Â Â Â Â T Lymphocyte Developmental BiologyÂ Â Â Â Â Â Â Â Â Ellen V. Rothenberg and Ameya Champhekar Â 14Â Â Â Â Â Â Â Peripheral T Lymphocyte Responses and FunctionÂ Â Â Marc K. Jenkins Â Section V. The Intersection of Innate and Adaptive Immunity Â 15Â Â Â Â Â Â Â The Innate Immune SystemÂ Â Â Luke A. J. Oâ€™Neill Â 16Â Â Â Â Â Â Â Dendritic Cells Â Â Â Â Â Â Â Â Â Â Â Michel C. NussenzweigÂ Â Â Â Â Â Â Â Â Â 17Â Â Â Â Â Â Â Natural Killer CellsÂ Â Â Â Wayne M. Yokoyama Â 18Â Â Â Â Â Â Â CD1d-restricted NKT Cells Albert S. Bendelac Â Â Â Â Â Â Â Â Â Â Â 19Â Â Â Â Â Â Â Macrophages and PhagocytosisÂ Â Â Â Â Â Â Â Â Siamon Gordon Â 20Â Â Â Â Â Â Â Granulocytes and Mast Cells Patrizia Scapini, Nicola Tamassia, Carlo Pucillo, and Marco A. CassatellaÂ Â Â 21Â Â Â Â Â Â Â The Major Histocompatibility Complex and its Proteins Â Â Â Â Â Â Â Â Â Â Â David H. MarguliesÂ Â Â Â 22Â Â Â Â Â Â Â Antigen Processing and Presentation Â Â Â Â Â Â Â Â Â Â Â Ted H. Hansen and Paul A. RocheÂ Â Â Â Â Section VI. Induction, Regulation, and Effector Functions of the Immune Response Â 23Â Â Â Â Â Â Â Immunogenicity and Antigen Structure Â Â Â Â Â Â Â Â Â Â Â Jay A. BerzofskyÂ Â Â Â Â Â Â Â 24Â Â Â Â Â Â Â Fc Receptors and Their Role in Immune Regulation and InflammationÂ Â Â Â Â Â Â Jeffrey V. Ravetch and Falk Nimmerjahn Â 25Â Â Â Â Â Â Â Type I Cytokines and Interferons Â Â Â Â Â Â Â Â Â Â Â Warren J. LeonardÂ Â Â Â Â Â 26Â Â Â Â Â Â Â Interleukin-1 Family Cytokines Â Â Â Â Â Â Â Â Â Â Â Charles A. Dinarello and Mihai G. NeteaÂ Â Â Â Â Â Â 27Â Â Â Â Â Â Â TNF-related Cytokines in Immunity Â Â Â Â Â Â Â Â Â Â Â Carl F. WareÂ Â Â Â 28Â Â Â Â Â Â Â Chemokines Â Â Â Â Â Â Â Â Â Â Â Philip M. MurphyÂ Â Â Â Â Â Â Â 29Â Â Â Â Â Â Â Helper T Cell Differentiation and Plasticity Â Â Â Â Â Â Â Â Â Â Â John J. Oâ€™SheaÂ Â Â Â Â Â Â Â Â Â Â Â 30Â Â Â Â Â Â Â Programmed Cell Death Â Â Â Â Â Â Â Â Â Â Â Andrew L. Snow and Michael J. LenardoÂ Â Â Â Â 31Â Â Â Â Â Â Â Immunological MemoryÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Shane Crotty, Susan M. Kaech, and Stephen P. SchoenbergerÂ Â Â Â Â Â Â Â Â Â 32Â Â Â Â Â Â Â Immunological Tolerance Â Â Â Â Â Â Â Â Â Â Â Pamela S. OhashiÂ Â Â Â Â Â Â Â 33Â Â Â Â Â Â Â Regulatory/Suppressor T Cells Â Â Â Â Â Â Â Â Â Â Â Ethan M. ShevachÂ Â Â Â Â Â Â 34Â Â Â Â Â Â Â Mucosal Immunity and Microbiome Â Â Â Â Â Â Â Â Â Â Â Yasmine BelkaidÂ Â Â Â Â Â Â Â Â 35Â Â Â Â Â Â Â Neurophysiological Reflex Mechanisms in ImmunologyÂ Â Â Â Â Â Chavan and Kevin J. Tracey Â 36Â Â Â Â Â Â Â ComplementÂ Â Â B. Paul Morgan Â 37Â Â Â Â Â Â Â Cell-mediated Cytotoxicity Â Â Â Â Â Â Â Â Â Â Â Judy LiebermanÂ Â Â Â Â Â Â Â Â Â Section VII. Immunity to Infectious Agents Â 38Â Â Â Â Â Â Â The Immune Response to Parasites Â Â Â Â Â Â Â Â Â Â Â Thomas A. Wynne, David L. Sacks, Alan Sher, and Eleanor M. Riley

Fundamental Immunology

Description

Features

About the Author(s)

Specs

Table of contents