Hemostasis and Thrombosis

• Victor J Marder MD
• Professor of Clinical Medicine, Director, Vascular Medicine Program, Los Angeles Orthopaedic Hospital/UCLA; Division of Hematology/Medical Oncology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA

• William C Aird MD
• Associate Professor of Medicine, Beth Israel Deaconness Medical Center, Boston, MA

• Joel S Bennett MD
• Professor of Medicine, University of Pennsylvania, Philadelphia, PA

• Sam Schulman MD
• Professor of Medicine, McMaster University, Hamilton, Ontario, Canada

• Gilbert C White II MD
• Executive Vice President for Research, Blood Center of Wisconsin, Milwaukee, WI 

• Edition: Sixth
• Product Format: Hardbound
• ISBN: 9781608319060
• Trim Size: 10.875 x 8.375
• Pages: 1592
• Pub Date: Nov 26, 2012
• Weight: 9.0

HEMOSTASIS AND THROMBOSIS: BASIC PRINCIPLES AND CLINICAL PRACTICE SIXTH EDITION     Part 1: Introduction to the Field of Hemostasis and Thrombosis     Chapter 1.  History of the Field William C. Aird and Gilbert C. White, II   Chapter 2.  Molecular Evolution of the Vertebrate Blood Coagulation System Marianne A. Grant and William C. Aird   Chapter 3.  Molecular and Clinical Genetics Lesley Everett, Karl C. Desch, and David Ginsburg   Chapter 4:  Coagulation Enzymology Sriram Krishnaswamy   Chapter 5: Cell Biology, Protein Processing, and Cell Signaling Randal J. Kaufman and Laura Popolo   Chapter 6: Cellular and Molecular Immunology Andrew H. Lichtman   Chapter 7:  Biostatistics and Epidemiology: The Basic Science of Clinical Research Kerry L. Lee   PART II: BASIC HEMOSTASIS AND THROMBOSIS SECTION A: COAGULATION & FIBRINOLYSIS   Chapter 8: Overview of Basic Coagulation and Fibrinolysis Gilbert C. White, II, Victor J. Marder, Sam Schulman, William C. Aird, and Joel S. Bennett   Chapter 9:  The Blood Coagulation Factors and Inhibitors: Complementary DNAs, Genes and Expression Dominic W. Chung, Wengfeng Xu, and Earl W. Davie   Chapter 10: Genetics of Coagulation Proteins Rodney M. Camire and Paris Margaritis   Chapter 11: Tissue Factor and the Initiation and Regulation (TFPI) of Coagulation George J. Broze, Jr. and James H. Morrissey   Chapter 12: Factors V and VIII Randal J. Kaufman, Philip J. Fay, Laura Popolo, and Thomas L. Ortel   Chapter 13: Structure and Function of von Willebrand Factor Sandra L. Haberichter and Robert R. Montgomery   Chapter 14: Structure and Function of Vitamin K-Dependent Coagulant and Anticoagulant Proteins Kanagasabai Vadivel, Amy E. Schmidt, Victor J. Marder, Sriram Krishnaswamy, and S. Paul Bajaj   Chapter 15A:  Factor XI Peter N. Walsh and David Gailani   Chapter 15B: The Factor XII-driven Plasma Contact System Thomas Renne   Chapter 16:  Fibrinogen Structure and Function John W. Weisel and Carl-Erik Dempfle Chapter 17: Factor XIII C\u00e9dric Duval, Helen Philippou, and Robert A. S. Ari\u00ebns   Chapter 18: Antithrombin and the Serpin Family Susan C. Bock   Chapter 19:  Protein C and S and Thrombomodulin System Laurent O. Mosnier and John H. Griffin Chapter 20: Plasminogen Activation and Regulation of Fibrinolysis Nuala A. Booth and Nicola J. Mutch   Chapter 21:  Inhibitors of Fibrinolysis Bj\u00f6rn Wiman and Anna Ågren   SECTION B: PLATELET BIOLOGY   Chapter 22: Overview of Platelet Structure and Function Joel S. Bennett and Gilbert C. White, II   Chapter 23:  Platelet Production: Cellular and Molecular Regulation Elisabeth Cramer Bord\u00e9 and William Vainchenker   Chapter 24: Megakaryocyte Structure and Platelet Biogenesis Joseph E. Italiano, Jr. and John H. Hartwig   Chapter 25:  Thrombopoietin Kenneth Kaushansky and Ian Hitchcock    Chapter 26A: Major Platelet Glycoproteins: GPIb-IX-V Michael C. Berndt, and Robert K. Andrews   Chapter 26B: Major Platelet Glycoproteins: GPIIb/IIIa Feng Ye and Mark H. Ginsberg   Chapter 27:  Platelet Glycoprotein Polymorphisms and Relationship to Function and Immunogenicity Thomas J. Kunicki and Diane J. Nugent   Chapter 28: The Basis for Platelet Adhesion Brian Savage and Zaverio M. Ruggeri   Chapter 29: Shear Effects on Platelets and the Vessel Wall in the Pathogenesis of Atherothrombosis David L. Bark Jr., Warwick S. Nesbitt, Angus K.T. Wong, and Shaun P. Jackson   Chapter 30: Platelets and Collagen Steve P Watson, Richard W Farndale, Masaaki Moroi, and Stephanie M Jung   Chapter 31: Integrin αIIb β3 and Platelet Aggregation Ana Kasirer-Friede, Kamila Bledzka, Jun Qin, , Edward F. Plow, and Sanford J. Shattil   Chapter 32:  Molecular Basis for Platelet Secretion Shaojing Ye and Sidney W. Whitehart   Chapter 33: Platelet Signal Transduction Charles S. Abrams and Lawrence F. Brass    Chapter 34:  Platelet Prostaglandin Metabolism Tilo Grosser and Garret A. FitzGerald   Chapter 35:  The Role of Platelets in Blood Coagulation Peter N. Walsh   Chapter 36:  Blood-Borne Microparticles Jos\u00e9 L\u00f3pez and Swaminathan Murugappan   SECTION C: VASCULAR BIOLOGY   William C. Aird   Chapter 37:  Overview of Vascular Biology William C. Aird   Chapter 38: Development of the Vasculature, Angiogenesis, Lymphangiogenesis Aernout Luttun and Peter Carmeliet   Chapter 39: Rheology and Vessel Wall Stress Peter F. Davies, Larry V. McIntire, and Juan M. Jim\u00e9nez   Chapter 40:  Nitric Oxide Bradley A. Maron and Thomas Michel Chapter 41:  Blood Vessel Wall in Health and Disease Keith R. Brunt, Sonya Hui, Jagdish Butany, and Mansoor Husain   Chapter 42:  Endothelial Cell Function William C. Aird   Chapter 43:  Role of Endothelium in Hemostasis Michael J. Krisinger and Edward M. Conway   Chapter 44:  Coagulation-Independent Signaling of the Extrinsic Coagulation Pathway Wolfram Ruf   Chapter 45:  Heparin and Vascular Proteoglycans Douglas M. Tollefsen and Lijuan Zhang   Chapter 46: Endothelial Cell-Blood Cell Interactions Klaus Ley   Chapter 47:  Leukocyte Function and Contribution to Disease Edith van de Vijver and Taco W. Kuijpers   Chapter 48: Laboratory Markers of Endothelial Cell Activation and Dysfunction Eduard Shantsila, Gregory Y.H. Lip, and Robert P. Hebbel   PART III:  DISORDERS OF COAGULATION, PLATELETS, AND VESSEL WALL SECTION A: BLEEDING DISORDERS COAGULATION & FIBRINOLYSIS   Chapter 49: Overview of Inherited Hemorrhagic Disorders Gilbert C. White, II, Harold R. Roberts, and Victor J. Marder   Chapter 50:  Differential Diagnosis of the Bleeding Patient Jill M. Johnsen and Barbara A. Konkle    Chapter 51: Clinical Manifestations and Therapy of Inherited and Acquired Hemophilia Edward G.D. Tuddenham   Chapter 52: von Willebrand Disease: Diagnosis, Classification, and Treatment J. Evan Sadler and David Lillicrap   Chapter 53:  Rare Inherited Coagulation Disorders Other than Hemophilia Pier Mannuccio Manucci, Massimo Franchini, and Flora Peyvandi   Chapter 54: Afibrogenemias and Dysfibrogenemias Dennis K. Galanakis   Chapter 55: Familial Multiple Coagulation Factor Deficiencies Bin Zhang and David Ginsburg   Chapter 56:  Clinical Disorders of Fibrinolysis Daphne Stewart, Charles W. Francis, and Victor J. Marder   Chapter 57: Acquired Disorders of Coagulation: The Immune Coagulopathies Charles RM Hay   Chapter 58:  Laboratory Markers of Coagulation and Fibrinolysis Kenneth A. Bauer and Helen A. Ireland   SECTION B: ACQUIRED & INHERITED PLATELET DISORDERS   Chapter 59: Overview of Acquired and Inherited Clinical Platelet Disorders Joel S. Bennett   Chapter 60: Differential Diagnosis of Thrombocytopenia Joel S. Bennett and Charles S. Abrams   Chapter 61:  Immune Thrombocytopenic Purpuraand Posttransfusion Purpura Howard A. Liebman, Douglas B. Cines, and James B. Bussel   Chapter 62: Drug-Induced Thrombocytopenia Richard H. Aster and James N. George   Chapter 63: Inherited Thrombocytopenias Paquita Nurden and Alan T. Nurden   Chapter 64: Acquired Nonimmune Thrombocytopenia Andreas Greinacher and Theodore E. Warkentin   Chapter 65:  Hereditary Disorders of Platelet Function Joel S. Bennett and A. Koneti Rao   Chapter 66: Acquired Disorders of Platelet Function A. Koneti Rao and Joe