Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry

Wilson and Gisvolds Textbook of Organic 9780781779296
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Publication Date: Mar 2, 2010
Availability: IN STOCK
Format: Book
Edition: Twelfth
ISBN/ISSN: 9780781779296
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For over half a century, Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry has served the discipline of medicinal chemistry for both graduate and undergraduate pharmacy and chemistry students as well as practicing pharmacists. Fully updated for the Twelfth Edition, the book begins with the fundamental principles of chemistry, biochemistry, and biology that underlie the discipline of medicinal chemistry. These principles are then applied to understanding the properties, mode of action, therapeutic applications, and limitations of various pharmaceutical agents. The subject matter is organized by pharmaceutical and therapeutic classes, providing a bridge between the basic sciences and clinical practice. The text contains many tables for quick reference to names, formulations, dosages, and applications. This edition includes chapter review questions and cases.

A companion website provides online updates of medicinal chemistry structures and an image bank for faculty.


--NEW!: Chapter Review Questions to reinforce concepts learned in each chapter
--NEW! Chapter Overview introduces students to the topic of each chapter
--NEW! Highlight color added to heighten book's visual appeal
--Logically organized by pharmaceutical and therapeutic class for quick, easy reference
--Plenty of tables for quick reference to names, formulations, dosages, and applications

About the Author(s)

  • John M Beale Jr., PhD
  • Associate Professor of Medicinal Chemistry, Division of Basic and Pharmaceutical Sciences, St. Louis College of Pharmacy, St. Louis, MO


  • Edition: Twelfth
  • Product Format: Hardbound
  • ISBN: 9780781779296
  • Trim Size: 8.375 x 10.875
  • Pages: 1008
  • Pub Date: Mar 2, 2010
  • Weight: 5.0

Table of contents

  1. Introduction
  2. Drug Design Strategies
  3. Metabolic Changes of Drugs and Related Organic Compounds
  4. Biotechnology and Drug Discovery
  5. Immunobiologicals
  6. Anti-infective
  7. Antimalarials
  8. Antibacterial Antibiotics
  9. Antiviral Agents
  10. Antineoplastic Agents
  11. Agents for Diagnostic Imaging
  12. Central Nervous System Depressant
  13. Central Dopaminergic Signaling Agents
  14. Anticonvulsants
  15. Central Nervous System Stimulants
  16. Adrenergic Agents
  17. Cholinergic Drugs
  18. Renal Acting Agents
  19. Cardiovascular Agents
  20. Hormone Related Disorders: Nonsteroidal Therapies
  21. Agents Treating Bone Disorders
  22. Anesthetics
  23. Histamine and Antihistaminic Agents
  24. Analgesics
  25. Steroids and Therapeutically Related Compounds
  26. Prostaglandins, Leukotrienes, and Other Eicosanoids
  27. Proteins, Enzymes and Peptide Hormones
  28. Vitamins and Related Compounds
  29. An Introduction to the Medicinal Chemistry of Herbs
Appendix, Calculated Log 0, Log D and pKa